CD22 anticorps (PerCP-Cy5.5)

N° du produit ABIN7674313

Cet anticorps anti-CD22 est un anticorps Souris Monoclonal détectant CD22 dans FACS. Adapté pour Souris.

Aperçu rapide pour CD22 anticorps (PerCP-Cy5.5) (ABIN7674313)

Antigène: CD22 (CD22 Molecule (CD22))

Reactivité: Souris

Hôte: Souris

Clonalité: Monoclonal

Conjugué: Cet anticorp CD22 est conjugé à/à la PerCP-Cy5.5

Application: Flow Cytometry (FACS)

Clone: Cy34-1

Détail du produit anti-CD22 anticorps (PerCP-Cy5.5)

Fonction: PerCP-Cy5.5 Anti-Mouse CD22 Antibody

Purification: 0

Pureté: 0

Isotype: IgG1, kappa

Information d'application

Indications d'application: Volume per test: 5μL. Each lot of this antibody is quality control tested by flow cytometric analysis. The amount of the reagent is suggested to be used 5 μL of antibody per test (million cells in 100 μL staining volume or per 100 μL of whole blood). Please check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use.

Restrictions: For Research Use only

Stockage

Format: Liquid

Buffer: PBS with 0. 1 % sodium azide, 1 % BSA, pH 7.3,

Agent conservateur: Sodium azide

Précaution d'utilisation: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Conseil sur la manipulation: Avoid repeated freeze / thaw cycles.

Stock: 4 °C

Stockage commentaire: 2-8°C for 12 months (Avoid repeated freeze / thaw cycles.)

Date de péremption: 12 months

Détails sur CD22

Antigène: CD22 (CD22 Molecule (CD22))

Autre désignation: CD22

Sujet:

Synonyms: Siglec2|B-cell receptor CD22|B-lymphocyte cell adhesion molecule|BL-CAM|CD22|Cd22|Lyb-8|Sialic acid-binding Ig-like lectin 2|Siglec-2|T-cell surface antigen Leu-14

Background: The Cy34.1 monoclonal antibody specifically binds to the B-lymphocyte differentiation antigen CD22 on strains having the Lyb-8.2 alloantigen (e.g., A, BALB/c, CBA, C3H/He, C57BL, C57L, C58, SJL, SWR, but not AKR, DBA/1, DBA/2, NZB, PL). CD22 is expressed at high levels on mature peripheral B lymphocytes (follicular and marginal zone), B-1 cells (CD5+ B cells), and plasma cells. It is a member of the Ig gene superfamily and associates with the B-cell antigen receptor. Its sialic acid- binding immunoglobulin-like lectin (siglec) extracellular region mediates B-cell adhesion to ligands on endothelial cells in the bone marrow. Its intracellular domain is phosphorylated after cross-linking of antigen receptor or MHC class II antigen. It is involved in negative regulation of B-cell activation and protection from autoimmunity. B-cell proliferative responses to LPS or anti-mouse Ig μ chain are augmented in the presence of Cy34.1 mAb.

Poids moléculaire: 0

ID gène: 12483

UniProt: P35329